Tetranuclear cationic open boxes non-covalently bind DNA major groove. By contrast, they covalently bind cysteine after ligand exchange reactions. In addition, these systems exhibit potent antitumour activity circumventing cisplatin resistance.
Molecular architecture of redox-active half-sandwich Ru(ii) cyclic assemblies : interactions with biomolecules and anticancer activity / F. Linares, E. Quartapelle Procopio, M.A. Galindo, M.A. Romero, J.A.R. Navarro, E. Barea. - In: CRYSTENGCOMM. - ISSN 1466-8033. - 12:8(2010 Aug), pp. 2343-2346. [10.1039/c002411b]
Molecular architecture of redox-active half-sandwich Ru(ii) cyclic assemblies : interactions with biomolecules and anticancer activity
E. Quartapelle Procopio;
2010
Abstract
Tetranuclear cationic open boxes non-covalently bind DNA major groove. By contrast, they covalently bind cysteine after ligand exchange reactions. In addition, these systems exhibit potent antitumour activity circumventing cisplatin resistance.
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