To identify molecular targets that interact with zosteric acid, a small-scale affinity purification of proteins from E. coli extracts on immobilized zosteric acid moieties was performed. According to the biological screening of the small library of molecules, p-aminocinnamic acid was selected for its covalent coupling to the affinity support. Functionalization of the solid support was successfully demonstrated by fluorescence analysis. The protein pull-down revealed that one protein bound to cinnamate coupled matrix. The identification of this protein is still in progress.

Antibiofilm activity of selected natural compounds / C. Cattò. ((Intervento presentato al 9. convegno Workshop. Doctorate in Chemistry, Biochemistry and Ecology of Plant Protection Products and Xenobiotics tenutosi a Milano nel 2014.

Antibiofilm activity of selected natural compounds

C. Cattò
Primo
2014-01

Abstract

To identify molecular targets that interact with zosteric acid, a small-scale affinity purification of proteins from E. coli extracts on immobilized zosteric acid moieties was performed. According to the biological screening of the small library of molecules, p-aminocinnamic acid was selected for its covalent coupling to the affinity support. Functionalization of the solid support was successfully demonstrated by fluorescence analysis. The protein pull-down revealed that one protein bound to cinnamate coupled matrix. The identification of this protein is still in progress.
Settore BIO/10 - Biochimica
Settore AGR/16 - Microbiologia Agraria
Antibiofilm activity of selected natural compounds / C. Cattò. ((Intervento presentato al 9. convegno Workshop. Doctorate in Chemistry, Biochemistry and Ecology of Plant Protection Products and Xenobiotics tenutosi a Milano nel 2014.
Conference Object
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/232078
Citazioni
  • ???jsp.display-item.citation.pmc??? ND
  • Scopus ND
  • ???jsp.display-item.citation.isi??? ND
social impact