By capitalizing on the different reactivity of nitrile N-oxides with isocyanides and amine, α-oximinoamidines, a so far elusive class of compounds, have been synthesized in a straightforward way by reacting isocyanides, syn-chlorooximes, and amines in a multicomponent fashion.
Isocyanide-mediated multicomponent synthesis of C-oximinoamidines / V. Mercalli, F. Meneghetti, G.C. Tron. - In: ORGANIC LETTERS. - ISSN 1523-7060. - 15:22(2013 Nov), pp. 5902-5905.
Isocyanide-mediated multicomponent synthesis of C-oximinoamidines
F. MeneghettiSecondo
;
2013
Abstract
By capitalizing on the different reactivity of nitrile N-oxides with isocyanides and amine, α-oximinoamidines, a so far elusive class of compounds, have been synthesized in a straightforward way by reacting isocyanides, syn-chlorooximes, and amines in a multicomponent fashion.
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