In a woman suffering from insulin-dependent diabetes mellitus, hypokalemic paralysis developed acutely following an episode of diabetes decompensation. During the treatment of this episode, as soon as serum potassium levels were restored to normal values, a marked increase in muscular excitability with an electromyographic picture of myotonia was observed. The patient showed signs of chronic muscle denervation that accounted for an increased sensitivity to potassium-induced depolarization and contraction and that might have been responsible for the appearance of myotonia during potassium repletion.
Myotonia induced by potassium repletion in a diabetic patient with secondary hypokalemic paralysis / P. Bertora, M.R. Caccia, A. Mangoni. - In: EUROPEAN NEUROLOGY. - ISSN 0014-3022. - 34:6(1994), pp. 341-343.
Myotonia induced by potassium repletion in a diabetic patient with secondary hypokalemic paralysis
P. BertoraPrimo
;A. MangoniUltimo
1994
Abstract
In a woman suffering from insulin-dependent diabetes mellitus, hypokalemic paralysis developed acutely following an episode of diabetes decompensation. During the treatment of this episode, as soon as serum potassium levels were restored to normal values, a marked increase in muscular excitability with an electromyographic picture of myotonia was observed. The patient showed signs of chronic muscle denervation that accounted for an increased sensitivity to potassium-induced depolarization and contraction and that might have been responsible for the appearance of myotonia during potassium repletion.
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