The in vitro evaluation of platelet aggregation is useful to diagnose platelet function disorders [1, 2]; in some laboratories, the test is also used to monitor antiplatelet treatment [3]. Traditionally, platelet aggregation is measured by light transmission aggregometry (LTA), which measures the changes in transmission of a beam of light through a sample of platelet-rich plasma (PRP) or platelet suspensions in buffer, which occur when platelets change shape and aggregate upon stimulation. As this technique has some disadvantages [2], novel methods were introduced to measure platelet aggregation in vitro.
Effect of platelet count on platelet aggregation measured by impedance aggregometry (Multiplate(™) analyser) and by light transmission aggregometry / E.A. Femia, M. Scavone, A. Lecchi, M. Cattaneo. - In: JOURNAL OF THROMBOSIS AND HAEMOSTASIS. - ISSN 1538-7933. - 11:12(2013 Dec), pp. 2193-2196. [10.1111/jth.12432]
Effect of platelet count on platelet aggregation measured by impedance aggregometry (Multiplate(™) analyser) and by light transmission aggregometry
E.A. FemiaPrimo
;M. ScavoneSecondo
;M. CattaneoUltimo
2013
Abstract
The in vitro evaluation of platelet aggregation is useful to diagnose platelet function disorders [1, 2]; in some laboratories, the test is also used to monitor antiplatelet treatment [3]. Traditionally, platelet aggregation is measured by light transmission aggregometry (LTA), which measures the changes in transmission of a beam of light through a sample of platelet-rich plasma (PRP) or platelet suspensions in buffer, which occur when platelets change shape and aggregate upon stimulation. As this technique has some disadvantages [2], novel methods were introduced to measure platelet aggregation in vitro.File | Dimensione | Formato | |
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