Cigarette smoking is associated with reduced pulmonary function and increased risk factors for cardiovascular disease. This randomized placebo-controlled double-blind study evaluated the effects of two different combinations of mixed fruit and vegetable juice powder concentrate (Juice Plus+, NSA, Collierville, TN) on heavy smokers. At baseline (T 0)and after 3 months’supplementation (T1), pulmonary function parameters and cardiovascular risk factors—that is, plasma total homocysteine (tHcy) with related B vitamins and cysteine (tCys) concentrations—were assessed in 75 apparently healthy smokers (aged 49.2 ± 10.6 years, >20 cigarettes/d, duration ≥10 years) randomized into 3 groups: placebo (P), fruit/vegetable (FV) and fruit/vegetable/berry (FVB). Results: T 0: most smokers showed abnormalities in tHcy and tCys concentrations. T 1: respiratory function was unchanged in P and slightly, but not significantly, improved in FV, whereas FVB showed a significant improvement in forced expiratory flow at 25% (FEF25; p < 0.0001 vs P and FV) and significant improvement in CO diffusion lung/alveolar volume (DLCO/VA). FV and FVB (50%) showed significant reduction in tHcy and tCys compared to T 0 ( p < 0.0001) and P ( p < 0.0001). Conclusions: At T 1, both supplemented groups, but to a greater extent the FVB group, showed improvements in some pulmonary parameters, cardiovascular risk factors, and folate status. The beneficial effects of Juice Plus+ supplementation could potentially help smokers, even if smoking cessation is advisable.
An encapsulated juice powder concentrate improves markers of pulmonary function and cardiovascular risk factors in heavy smokers / F. Bamonti, M. Pellegatta, C. Novembrino, L. Vigna, R. De Giuseppe, F. de Liso, D. Gregori, C. Della Noce, L. Patrini, G. Schiraldi, P. Bonara, L. Calvelli, R. Maiavacca, G. Cighetti. - In: JOURNAL OF THE AMERICAN COLLEGE OF NUTRITION. - ISSN 0731-5724. - 32:1(2013 Apr), pp. 18-25.
|Titolo:||An encapsulated juice powder concentrate improves markers of pulmonary function and cardiovascular risk factors in heavy smokers|
BAMONTI, FABRIZIA (Primo)
CIGHETTI, GIULIANA MARIA (Ultimo)
|Parole Chiave:||cysteine; folate; homocysteine; nutraceutical; tobacco|
|Settore Scientifico Disciplinare:||Settore BIO/10 - Biochimica|
Settore BIO/12 - Biochimica Clinica e Biologia Molecolare Clinica
|Data di pubblicazione:||apr-2013|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1080/07315724.2013.767652|
|Appare nelle tipologie:||01 - Articolo su periodico|