We describe a patient with acute lymphoblastic leukaemia who developed rhinocerebral zygomycosis during the aplastic phase induced by antineoplastic chemotherapy. The patient was treated with fluconazole intravenously (400 mg daily) for 30 days and underwent surgical debridement. As a result of this treatment a complete remission of the zygomycosis-associated symptoms was observed. The possibility of treating zygomycosis with fluconazole is discussed.

Rhinocerebral zygomycosis in acute lymphoblastic leukaemia / S. Sica, G. Morace, L.M. La Rocca, B. Etuk, A. Di Mario, L. Pagano, G. Zini, S. Rutella, G. Leone. - In: MYCOSES. - ISSN 0933-7407. - 36:9-10(1993 Sep), pp. 289-291.

Rhinocerebral zygomycosis in acute lymphoblastic leukaemia

G. Morace
Secondo
;
1993

Abstract

We describe a patient with acute lymphoblastic leukaemia who developed rhinocerebral zygomycosis during the aplastic phase induced by antineoplastic chemotherapy. The patient was treated with fluconazole intravenously (400 mg daily) for 30 days and underwent surgical debridement. As a result of this treatment a complete remission of the zygomycosis-associated symptoms was observed. The possibility of treating zygomycosis with fluconazole is discussed.
Akute lymphoblastische Leukamie; Amphotericin B; Antimykotische Chemotherapie; Fluconazol; Zygomykose
Settore MED/07 - Microbiologia e Microbiologia Clinica
Settore MED/15 - Malattie del Sangue
set-1993
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/228087
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