Abstract The last 10 years witnessed a considerable increase in our knowledge of brain function in survivors to severe brain injuries with disorders of consciousness (DOC). At the same time, a growing interest developed for the use of functional neuroimaging as a new diagnostic tool in these patients. In this context, particular attention has been devoted to connectivity studies-as these, more than measures of brain metabolism, may be more appropriate to capture the dynamics of large populations of neurons. Here, we will review the pros and cons of various connectivity methods as potential diagnostic tools in brain-damaged patients with DOC. We will also discuss the relevance of the study of the level versus the contents of consciousness in this context.

Brain connectivity in disorders of consciousness / M. Boly, M. Massimini, M. I. Garrido, O. Gosseries, Q. Noirhomme, S. Laureys, A. Soddu. - In: BRAIN CONNECTIVITY. - ISSN 2158-0014. - 2:1(2012), pp. 1-10. [10.1089/brain.2011.0049]

Brain connectivity in disorders of consciousness

M. Massimini;
2012

Abstract

Abstract The last 10 years witnessed a considerable increase in our knowledge of brain function in survivors to severe brain injuries with disorders of consciousness (DOC). At the same time, a growing interest developed for the use of functional neuroimaging as a new diagnostic tool in these patients. In this context, particular attention has been devoted to connectivity studies-as these, more than measures of brain metabolism, may be more appropriate to capture the dynamics of large populations of neurons. Here, we will review the pros and cons of various connectivity methods as potential diagnostic tools in brain-damaged patients with DOC. We will also discuss the relevance of the study of the level versus the contents of consciousness in this context.
Settore BIO/09 - Fisiologia
Settore MED/26 - Neurologia
BRAIN CONNECTIVITY
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/227220
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