Serum antinuclear (ANA), mitochondrial (AMA) and smooth muscle (SMA) antibody have been measured in 130 patients with Australia antigen a antibody, and acute and chronic hepatitis. In patients with acute hepatitis, persistent hepatitis, postnecrotic cirrhosis these indices failed to show any correlation. In the group of patients with chronic aggressive hepatitis the incidence of Au was 70%, ANA 10%, AMA 3%, SMA 33%; Au negative patients had higher incidence of autoantibodies, mainly SMA (45%) and much higher titers of SMA than Au positive patients in whom SMA was 29%. No patient with primary biliary cirrhosis was Australia positive; the incidence of AMA was 90%.

Autoantibodies and Australia antigen in acute and chronic liver / S.R. Fargion, E. Del Ninno, M.D. Cappellini, G. Fiorelli. - In: MINERVA MEDICA. - ISSN 0026-4806. - 65:13(1974 Feb 21), pp. 723-728.

Autoantibodies and Australia antigen in acute and chronic liver

S.R. Fargion
Primo
;
E. Del Ninno
Secondo
;
M.D. Cappellini
Penultimo
;
G. Fiorelli
Ultimo
1974-02-21

Abstract

Serum antinuclear (ANA), mitochondrial (AMA) and smooth muscle (SMA) antibody have been measured in 130 patients with Australia antigen a antibody, and acute and chronic hepatitis. In patients with acute hepatitis, persistent hepatitis, postnecrotic cirrhosis these indices failed to show any correlation. In the group of patients with chronic aggressive hepatitis the incidence of Au was 70%, ANA 10%, AMA 3%, SMA 33%; Au negative patients had higher incidence of autoantibodies, mainly SMA (45%) and much higher titers of SMA than Au positive patients in whom SMA was 29%. No patient with primary biliary cirrhosis was Australia positive; the incidence of AMA was 90%.
Acute Disease ; Antibodies, Antinuclear ; Autoantibodies ; Chronic Disease ; Hepatitis ; Hepatitis A ; Hepatitis B Antigens ; Humans ; Liver Cirrhosis ; Muscle, Smooth ; Stomach ; Thyroid Gland
Settore MED/09 - Medicina Interna
Article (author)
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate

Caricamento pubblicazioni consigliate

I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.

Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/226666
Citazioni
  • ???jsp.display-item.citation.pmc??? 0
  • Scopus 1
  • ???jsp.display-item.citation.isi??? 1
social impact