Solvent- and Ligand-Free Palladium-Catalyzed Amination of Aryl Halides

An environmentally friendly and economically favorable approach to the formation of C-N bonds is presented. The methodology is particularly interesting in that the reaction is realized under both solvent- and ligand-free conditions and involves the use of a low loading of a palladium catalyst dispersed with the reactants on a suitable solid support. The reaction proceeds rapidly under microwave irradiation.