PURPOSE: To report the results of carotid artery stenting (CAS) in symptomatic patients (stroke/transient ischemic attack) after recent percutaneous transluminal coronary angioplasty (PTCA) for acute coronary syndrome (ACS). METHODS: Between January 2009 and July 2011, 28 consecutive patients (18 women; mean age 66 years, range 42-82) underwent protected CAS for symptomatic carotid stenosis following recent PTCA that included bare or drug-eluting stents requiring uninterrupted dual antiplatelet therapy. Primary technical success, neurological complications, major adverse cardiovascular events, and death were evaluated at 30 days and over midterm follow-up. RESULTS: Technical success was 96%; 1 patient suffered a nonfatal major stroke (3.5% 30-day stroke rate) during the procedure. During a median 21.6-month follow-up, 4 (14%) patients died of myocardial infarction (all diabetic smokers with ejection fractions <40%), but there were no new neurological events. Estimated survival was 89.3% at 2 years. Further coronary interventions were performed in 2 diabetic patients with a body mass index >34 kg/m(2). CONCLUSION: This preliminary experience demonstrated that CAS is a reasonable, safe, and effective treatment for patients with symptomatic carotid artery stenosis who were recently treated with coronary stents requiring uninterrupted dual antiplatelet therapy.
Carotid artery stenting in patients with acute coronary syndrome : a possible primary therapy for symptomatic carotid stenosis / R. Casana, A. Halliday, P. Bianchi, E. Fresa, V. Silani, G. Parati, S. Blengino, L. Cireni, L. Adobbati, L. Calvillo, V.S. Tolva. - In: JOURNAL OF ENDOVASCULAR THERAPY. - ISSN 1526-6028. - 20:4(2013 Aug), pp. 546-551.
|Titolo:||Carotid artery stenting in patients with acute coronary syndrome : a possible primary therapy for symptomatic carotid stenosis|
|Parole Chiave:||carotid artery stenting; carotid stenosis; cerebral protection; coronary angioplasty; coronary artery disease; myocardial infarction; percutaneous coronary intervention; stroke|
|Settore Scientifico Disciplinare:||Settore MED/26 - Neurologia|
Settore MED/22 - Chirurgia Vascolare
Settore ING-INF/06 - Bioingegneria Elettronica e Informatica
Settore MED/11 - Malattie dell'Apparato Cardiovascolare
|Data di pubblicazione:||ago-2013|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1583/13-4244.1|
|Appare nelle tipologie:||01 - Articolo su periodico|