This study was conducted to evaluate whether ultrasound characteristics of thyroid nodules with a known cytologic diagnosis of "follicular pattern" (indicative of follicular hyperplasia, follicular adenoma or follicular carcinoma) can be used to define a nodule malignancy score to limit surgery to selected, higher-risk cases. In pre-operative ultrasound results of patients diagnosed with a "follicular pattern" on cytology who subsequently underwent surgery, each nodule feature was given a score from 0 (most likely benign) to 2 (most likely malignant), resulting in a total score ranging from 0 to 11. The total nodule score (total malignancy score) was then compared with the definitive histologic diagnosis. According to our results, surgery is advisable in patients with score ≥4 (79% of carcinomas), ultrasound follow-up seems to be appropriate for patients with a score of 3 (21% of carcinomas) and no action is recommended for patients with score <3 (only benign nodules).
Management of thyroid follicular proliferation : an ultrasound-based malignancy score to opt for surgical or conservative treatment / G. Pompili, S. Tresoldi, A. Primolevo, L. De Pasquale, G. Di Leo, G. Cornalba. - In: ULTRASOUND IN MEDICINE AND BIOLOGY. - ISSN 0301-5629. - 39:8(2013 Aug), pp. 1350-1355.
|Titolo:||Management of thyroid follicular proliferation : an ultrasound-based malignancy score to opt for surgical or conservative treatment|
TRESOLDI, SILVIA (Secondo)
CORNALBA, GIANPAOLO (Ultimo)
|Parole Chiave:||Cytodiagnosis; Diagnostic imaging; Fine-needle biopsy; Follicular thyroid carcinoma; Thyroid nodule; Ultrasound|
|Settore Scientifico Disciplinare:||Settore MED/36 - Diagnostica per Immagini e Radioterapia|
|Data di pubblicazione:||ago-2013|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1016/j.ultrasmedbio.2013.02.464|
|Appare nelle tipologie:||01 - Articolo su periodico|