Epidemiological studies have suggested that aspirin may have a protective effect against prostate cancer, but the evidence is still limited and inconsistent The role of aspirin in prostate cancer risk was analysed in a multicentric case-control study conducted in Italy between 1991 and 2002, including 1261 incident cases of carcinoma of the prostate and 1131 hospital controls. A total of 115 (9.1%) cases versus 90 (8.0%) controls reported regular aspirin use. The multivariate odds ratio (OR) for regular aspirin users was 1.10 (95% confidence interval (95% CI) 0.81-1.50). No relation was found with duration of use (OR= 1.03 for < 5 years, and 1.17 for &rt;= 5 years) and time since first use (OR= 1.03 for < 10 years, and 1.35 for &rt;= 10 years). These findings do not support a protective role of regular aspirin use on prostate cancer risk.
Aspirin and the risk of prostate cancer / C. Bosetti, R. Talamini, E. Negri, S. Franceschi, M. Montella, C. La Vecchia. - In: EUROPEAN JOURNAL OF CANCER PREVENTION. - ISSN 0959-8278. - 15:1(2006 Feb), pp. 43-45.
Aspirin and the risk of prostate cancer
E. Negri;C. La VecchiaUltimo
2006
Abstract
Epidemiological studies have suggested that aspirin may have a protective effect against prostate cancer, but the evidence is still limited and inconsistent The role of aspirin in prostate cancer risk was analysed in a multicentric case-control study conducted in Italy between 1991 and 2002, including 1261 incident cases of carcinoma of the prostate and 1131 hospital controls. A total of 115 (9.1%) cases versus 90 (8.0%) controls reported regular aspirin use. The multivariate odds ratio (OR) for regular aspirin users was 1.10 (95% confidence interval (95% CI) 0.81-1.50). No relation was found with duration of use (OR= 1.03 for < 5 years, and 1.17 for &rt;= 5 years) and time since first use (OR= 1.03 for < 10 years, and 1.35 for &rt;= 10 years). These findings do not support a protective role of regular aspirin use on prostate cancer risk.File | Dimensione | Formato | |
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