Core histones are the building block of chromatin and among the most highly conserved proteins in eukaryotes. The related "deviant" histones share the histone-fold domain, and serve various roles in DNA metabolism. We provide here a structural and functional outlook of H2A/H2B-like deviant histones in transcription, replication and remodeling.

The H2A/H2B-like histone-fold domain proteins at the crossroad between chromatin and different DNA metabolisms / N. Gnesutta, M. Nardini, R. Mantovani. - In: TRANSCRIPTION. - ISSN 2154-1264. - 4:3(2013), pp. 114-119.

The H2A/H2B-like histone-fold domain proteins at the crossroad between chromatin and different DNA metabolisms

N. Gnesutta
Primo
;
M. Nardini
Secondo
;
R. Mantovani
Ultimo
2013

Abstract

Core histones are the building block of chromatin and among the most highly conserved proteins in eukaryotes. The related "deviant" histones share the histone-fold domain, and serve various roles in DNA metabolism. We provide here a structural and functional outlook of H2A/H2B-like deviant histones in transcription, replication and remodeling.
H2A/H2B ; NC2 ; NF-Y ; TAF4/12 ; chromatin ; chromatin remodeling complex ; histone-fold ; nucleosome ; posttranslational modifications ; transcription factors
Settore BIO/10 - Biochimica
Settore BIO/18 - Genetica
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/223761
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