Blood pressure (BP) of a healthy 37-yr-old male traveling from Milan to Houston was monitored for 36 h before the flight and continued for 5 d after the arrival. The rhythmometric analysis of BP data was made to investigate the rate of adaptation to a rapid rest-activity cycle shift. Since two trips were evaluated, during the second one the subject took melatonin (3 mg) before the nocturnal rest. In the first trip the BP circadian rhythm synchronization occurred on the 5th day. In the second trip melatonin promoted an immediate but unstable adaptation to the new rest-activity cycle.

Resynchronization of blood pressure circadian rhythm after westward trans-7-meridian flight with and without melatonin treatment / P. Barattini, C. Dolci, A. Montaruli, E. Roveda, F. Carandente. - In: AVIATION, SPACE, AND ENVIRONMENTAL MEDICINE. - ISSN 0095-6562. - 72:3(2001), pp. 221-224.

Resynchronization of blood pressure circadian rhythm after westward trans-7-meridian flight with and without melatonin treatment

C. Dolci
Secondo
;
A. Montaruli;E. Roveda
Penultimo
;
F. Carandente
Ultimo
2001

Abstract

Blood pressure (BP) of a healthy 37-yr-old male traveling from Milan to Houston was monitored for 36 h before the flight and continued for 5 d after the arrival. The rhythmometric analysis of BP data was made to investigate the rate of adaptation to a rapid rest-activity cycle shift. Since two trips were evaluated, during the second one the subject took melatonin (3 mg) before the nocturnal rest. In the first trip the BP circadian rhythm synchronization occurred on the 5th day. In the second trip melatonin promoted an immediate but unstable adaptation to the new rest-activity cycle.
transmeridian flight ; circadian rhythm ; BP ; melatonin ; readjustment
Settore MED/09 - Medicina Interna
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/22361
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