Historical bias has favored fluid restriction in patients with brain pathology. The efficacy of fluid restriction on brain edema remains unproven, and the consequences of fluid restriction, if pursued to the point of hypovolemia, can be devastating. Perioperative fluid management has undergone significant advances over the past few decades, and medical practice needs to be guided by physiologic principles (osmotic pressure, osmolarity and osmolality, colloidoncotic pressure, Starling's hypothesis, interstitial clearance, hydrostatic forces and interstitial compliance and blood-brain barrier function).

Fluid management during neurosurgical procedures / C. Tommasino, V. Picozzi - In: A practical approach to neuroanesthesia / [a cura di] P.D. Morgan, S.G. Soriano, T.B. Sloan. - Prima edizione. - Baltimore : Lippincott Williams & Wilkins, 2013. - ISBN 9781451173154. - pp. 22-36

Fluid management during neurosurgical procedures

C. Tommasino
Primo
;
V. Picozzi
Ultimo
2013

Abstract

Historical bias has favored fluid restriction in patients with brain pathology. The efficacy of fluid restriction on brain edema remains unproven, and the consequences of fluid restriction, if pursued to the point of hypovolemia, can be devastating. Perioperative fluid management has undergone significant advances over the past few decades, and medical practice needs to be guided by physiologic principles (osmotic pressure, osmolarity and osmolality, colloidoncotic pressure, Starling's hypothesis, interstitial clearance, hydrostatic forces and interstitial compliance and blood-brain barrier function).
neurosurgical patients ; brain physiology ; brain pathology ; brain edema ; crystalloids ; colloids ; hypertonic solutions ; glucose ; diabetes insipidus ; syndrome of inappropriate antidiuretic hormone secretion ; cerebral salt wasting syndrome
Settore MED/41 - Anestesiologia
Settore MED/26 - Neurologia
Settore MED/27 - Neurochirurgia
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/223607
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