Diabetes mellitus is a metabolic disease possi- ble to treat via pancreas/islet transplantation but most immunosuppressive drugs are diabeto- genic. In this letter, we review current up to date methods to assess insulin action and secretion (using the surrogate indexes) suggesting their use in large studies in populations of pancreas/ islets transplanted patients.
Immunosuppressive therapy in pancreas and islet transplant : Need for simultaneous assessment of insulin sensitivity and secretion / S. Benedini, A. Caumo, I. Terruzzi, L. Luzi. - In: JOURNAL OF DIABETES MELLITUS. - ISSN 2160-5831. - 3:3(2013 Aug), pp. 156-160. [10.4236/jdm.2013.33024]
Immunosuppressive therapy in pancreas and islet transplant : Need for simultaneous assessment of insulin sensitivity and secretion
S. BenediniPrimo
;A. CaumoSecondo
;I. TerruzziPenultimo
;L. LuziUltimo
2013
Abstract
Diabetes mellitus is a metabolic disease possi- ble to treat via pancreas/islet transplantation but most immunosuppressive drugs are diabeto- genic. In this letter, we review current up to date methods to assess insulin action and secretion (using the surrogate indexes) suggesting their use in large studies in populations of pancreas/ islets transplanted patients.
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