Levels of radioactive caffeine and metabolites, after intra muscular injection of 1-methyl14C caffeine to pregnant rats, have been measured in maternal and fetal brains and livers at various time intervals. Caffeine and metabolites diffuse into fetal tissues and accumulate in fetal brain.
Accumulation of caffeine and its metabolites in rat fetal brain and liver / C. Galli, P.F. Spano, K. Szyszka. - In: PHARMACOLOGICAL RESEARCH COMMUNICATIONS. - ISSN 0031-6989. - 7:3(1975 May), pp. 217-221.
Accumulation of caffeine and its metabolites in rat fetal brain and liver
C. GalliPrimo
;
1975
Abstract
Levels of radioactive caffeine and metabolites, after intra muscular injection of 1-methyl14C caffeine to pregnant rats, have been measured in maternal and fetal brains and livers at various time intervals. Caffeine and metabolites diffuse into fetal tissues and accumulate in fetal brain.
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