Platelet-Rich Fibrin and Xenogeneic Bone Graft for Sinus Elevation

AIM: The aim of the present work was to evaluate the potential effect of Platelet-Rich Fibrin (PRF) in combination with anorganic bovine bone (Bioss®) to enhance bone regeneration in sinus augmentation procedure, by means of histologic and histomorphometric examinations of bone biopsies. METHODS and MATERIAL: This study involved a total of 8 sinus floor elevations being carried out on 4 patients. In 4 sites of study group PRF was associated to anorganic bovine bone Bioss®. In the other 4 sites (control group) was used only Bioss®. The PRF has been obtained with the aid of a centrifuge (Hettich Zentrifugen® D-78532). After an average healing phase of 4.2 months, for the study group and 6.7 months for the control group bone specimens were harvested from the elevated sinus, during implant placement. RESULTS: Radiographic, histologic and histomorphometric evaluations showed a newly formed bone by a similar quantity in both study and control groups. CONCLUSIONS: Platelet-Rich-Fibrin associated to Bioss® during sinus elevation reduced the healing time before implant insertion.