We report the case of a 66 years old woman with histological diagnosis of muscle-invasive high grade transitional cell carcinoma and clinical diagnosis (TC) of metastatic disease treated with a platinum based combination chemotherapy obtaining a pathologic complete response. Neoadjuvant chemotherapy for bladder cancer even with its limitations regarding patients selection, current development of surgical technique and current chemotherapy combination has shown to improve overall survival by 5-7% at 5 years and should be considered in muscle invasive bladder cancer, irrespective of definitive treatment.

Neoadjuvant chemotherapy for invasive bladder cancer : an interesting case report / D. Abed El Rahman, V. Deliu Matei, G. Musi, D. Bottero, A. Brescia, G. Galasso, F. Mazzoleni, O. De Cobelli. - In: ARCHIVIO ITALIANO DI UROLOGIA ANDROLOGIA. - ISSN 1124-3562. - 84:3(2012), pp. 167-170.

Neoadjuvant chemotherapy for invasive bladder cancer : an interesting case report

D. Abed El Rahman;G. Musi;O. De Cobelli
2012

Abstract

We report the case of a 66 years old woman with histological diagnosis of muscle-invasive high grade transitional cell carcinoma and clinical diagnosis (TC) of metastatic disease treated with a platinum based combination chemotherapy obtaining a pathologic complete response. Neoadjuvant chemotherapy for bladder cancer even with its limitations regarding patients selection, current development of surgical technique and current chemotherapy combination has shown to improve overall survival by 5-7% at 5 years and should be considered in muscle invasive bladder cancer, irrespective of definitive treatment.
Bladder cancer; Chemotherapy; Neoadjuvant therapy
Settore MED/24 - Urologia
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Utilizza questo identificativo per citare o creare un link a questo documento: http://hdl.handle.net/2434/219715
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