Radiation therapy (RT) is one of the treatment options for prostate cancer (PCa). Transperineal low-dose rate brachytherapy (BT) is another safe and effective technique for low-risk PCa. Recurrence after RT for localized PCa can be defined by a PSA value of 2 ng/mL above the nadir after RT, and biochemical recurrence (BCR) rate after RT is 40-60 %. In case of radiorecurrent PCa, treatment options include salvage radical prostatectomy (RP), cryo-therapy, high-intensity focused ultrasound (HIFU), and salvage BT. Only salvage RP has cancer control results for over 10-year follow-up in a substantial portion of patients (30-40 %). However, salvage RP is technically demanding, and experienced surgeons are needed; in fact, RT-induced cystitis, fibrosis, and tissue plane obliteration can lead to significant complications, such as rectal injuries, anastomot-ic stricture, and urinary incontinence. This review describes indications, oncologic and functional outcomes, surgical techniques, and complications of salvage robot-assisted RP.
|Titolo:||Current status of salvage robot-assisted laparoscopic prostatectomy for radiorecurrent prostate cancer|
COZZI, GABRIELE (Secondo)
|Parole Chiave:||Brachytherapy; Endourology; Prostate cancer; Radiation failure; Radiation therapy; Radiorecurrent prostate cancer; Recurrence; Salvage robot-assisted laparoscopic prostatectomy; sRALP; Surgery|
|Settore Scientifico Disciplinare:||Settore MED/24 - Urologia|
|Data di pubblicazione:||2012|
|Digital Object Identifier (DOI):||10.1007/s11934-012-0245-1|
|Appare nelle tipologie:||01 - Articolo su periodico|