An information domain approach to the assessment of causality was applied to the beat-to-beat variability of heart period and systolic arterial pressure to test the open loop condition along baroreflex in heart transplant recipients. The closed loop between heart period and systolic arterial pressure was detected as open at the level of the baroreflex if systolic arterial pressure is more easily predictable from heart period than vice versa according to a conditional entropy approach. We found that in short-term heart transplant (STHT) recipients (less than 2 years after transplantation) the closed loop between heart period and systolic arterial pressure was open at the level of baroreflex. Baroreflex appeared to be involved in the heart period regulation in long-term heart transplant (LTHT) recipients (more than 2 years after transplantation). The significant linear correlation of causality index on the number of months after transplantation suggests that baroreflex control recovers after transplantation
RR-SAP causality in heart transplant recipients / A. Porta, V. Magagnin, T. Bassani, E. Tobaldini, N. Montano, P. van de Borne - In: Engineering in Medicine and Biology Society (EMBC), 2010 Annual International Conference of the IEEE[s.l] : IEEE Service Center, 2010. - ISBN 978-1-4244-4123-5. - pp. 3449-3452 (( Intervento presentato al 32. convegno EMBC tenutosi a Buenos Aires nel 2010 [10.1109/IEMBS.2010.5627868].
RR-SAP causality in heart transplant recipients
A. PortaPrimo
;E. Tobaldini;N. MontanoPenultimo
;
2010
Abstract
An information domain approach to the assessment of causality was applied to the beat-to-beat variability of heart period and systolic arterial pressure to test the open loop condition along baroreflex in heart transplant recipients. The closed loop between heart period and systolic arterial pressure was detected as open at the level of the baroreflex if systolic arterial pressure is more easily predictable from heart period than vice versa according to a conditional entropy approach. We found that in short-term heart transplant (STHT) recipients (less than 2 years after transplantation) the closed loop between heart period and systolic arterial pressure was open at the level of baroreflex. Baroreflex appeared to be involved in the heart period regulation in long-term heart transplant (LTHT) recipients (more than 2 years after transplantation). The significant linear correlation of causality index on the number of months after transplantation suggests that baroreflex control recovers after transplantation
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