Mimics of oligosaccharides capable of interfering with lectin activity are currently being pursued by a number of groups in an effort to produce tools for glycobiology and to design antagonists of medically relevant lectins. The field is reviewed in this chapter. After a brief overview of the state of the art, examples from our and others' studies on the dendritic cell receptor DC-SIGN are illustrated.
Carbohydrate Mimics and Lectins : A Source of New Drugs and Therapeutic Opportunities [Recensione] / J.J. Reina, A. Bernardi. - In: MINI-REVIEWS IN MEDICINAL CHEMISTRY. - ISSN 1389-5575. - 12:14(2012), pp. 1434-1442.
Carbohydrate Mimics and Lectins : A Source of New Drugs and Therapeutic Opportunities
J.J. ReinaPrimo
;A. BernardiUltimo
2012
Abstract
Mimics of oligosaccharides capable of interfering with lectin activity are currently being pursued by a number of groups in an effort to produce tools for glycobiology and to design antagonists of medically relevant lectins. The field is reviewed in this chapter. After a brief overview of the state of the art, examples from our and others' studies on the dendritic cell receptor DC-SIGN are illustrated.
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