The catalytic osmylation of a series of 4-(2-styryl)-azetidin-2-ones carried out in the presence of dihydroquinidine-p-chlorobenzoate opens access to synthetically useful precursors of β-lactam antibiotics of high ennatiomeric purity (ee up to 97%).

SYNTHESIS OF BETA-LACTAMS OF HIGH ENANTIOMERIC PURITY BY CHIRAL LIGAND ACCELERATED OSMYLATION OF RACEMIC 4-(2-STYRYL)-AZETIDIN-2-ONES / R. Annunziata, M. Benaglia, M. Cinquini, F. Cozzi, F. Ponzini. - In: BIOORGANIC & MEDICINAL CHEMISTRY LETTERS. - ISSN 0960-894X. - 3:11(1993), pp. 2397-2402.

SYNTHESIS OF BETA-LACTAMS OF HIGH ENANTIOMERIC PURITY BY CHIRAL LIGAND ACCELERATED OSMYLATION OF RACEMIC 4-(2-STYRYL)-AZETIDIN-2-ONES

R. Annunziata
Primo
;
M. Benaglia
Secondo
;
M. Cinquini;F. Cozzi
Penultimo
;
1993

Abstract

The catalytic osmylation of a series of 4-(2-styryl)-azetidin-2-ones carried out in the presence of dihydroquinidine-p-chlorobenzoate opens access to synthetically useful precursors of β-lactam antibiotics of high ennatiomeric purity (ee up to 97%).
Settore CHIM/06 - Chimica Organica
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/213572
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