The authors studied the effect that a subinhibitory concentration of Clindamycin has on adherence of coagulase negative S. epidermidis to surgical nets. Clindamycin, as expected, interferes with the adhesivity to the nets of coagulase-negative S. epidermidis slime producing when sub-MICs are used. The documentation obtained by scanning electron microscope, after treatment of the strains with doses of Clindamycin equal to 1/6 of the MIC after 3 and 6 hours, confirms the anti-adherent effect of the antibiotic.
Effect of clindamycin on adherence of coagulase-negative Staphilococcus to surgical nets / M. Gismondo, G. Chisari, A. Lo Bue, G. Lupo. - In: IL GIORNALE DI CHIRURGIA. - ISSN 0391-9005. - (1990).
Effect of clindamycin on adherence of coagulase-negative Staphilococcus to surgical nets
M. GismondoPrimo
;
1990
Abstract
The authors studied the effect that a subinhibitory concentration of Clindamycin has on adherence of coagulase negative S. epidermidis to surgical nets. Clindamycin, as expected, interferes with the adhesivity to the nets of coagulase-negative S. epidermidis slime producing when sub-MICs are used. The documentation obtained by scanning electron microscope, after treatment of the strains with doses of Clindamycin equal to 1/6 of the MIC after 3 and 6 hours, confirms the anti-adherent effect of the antibiotic.
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