An 18-month-old male basset hound was presented with vomiting, diarrhoea and depression. Abdominal ultrasonography revealed a mass in the left kidney. An ultrasound-guided core-biopsy indicated aggregates of spindle cells, but did not allow a definitive diagnosis. Nephrectomy was performed after a period of six months, when ultrasound examination revealed a slight increase in mass dimensions. Histologically the mass was composed of neoplastic spindle cells forming interlacing fascicles, bundles and whorls, within a loose myxoid to dense collagenous stroma. Immunohistochemically neoplastic cells were positive for vimentin and smooth muscle actin. Based on these findings the tumour was diagnosed as a congenital mesoblastic nephroma, classical variant. After a two-and-a-half-year follow-up the dog was clinically healthy, indicating a benign behaviour. To the authors' knowledge, this report describes the first case of canine congenital mesoblastic nephroma successfully treated surgically, with a reasonable postsurgical follow-up.
Congenital mesoblastic nephroma in a young basset hound dog / S. Soldati, E. Radaelli, A. Mazzuti, E. Scanziani. - In: JOURNAL OF SMALL ANIMAL PRACTICE. - ISSN 0022-4510. - 53:12(2012 Nov), pp. 709-713.
|Titolo:||Congenital mesoblastic nephroma in a young basset hound dog|
RADAELLI, ENRICO (Secondo)
SCANZIANI, EUGENIO (Ultimo)
|Parole Chiave:||mesenchymal tumor; beagle dog; children; turnours|
|Settore Scientifico Disciplinare:||Settore VET/03 - Patologia Generale e Anatomia Patologica Veterinaria|
|Data di pubblicazione:||nov-2012|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1111/j.1748-5827.2012.01289.x|
|Appare nelle tipologie:||01 - Articolo su periodico|