BACKGROUND: Donovanosis is a chronic bacterial illness, progressive and indolent, which normally attacks the skin and mucous membranes in the genital and perigenital regions. CASE: An 18-year-old pregnant female presented with large, hypertrophic lesions in the ano-genital region. HIV serology was negative. Pap smear revealed a CIN 1 associated with HPV infection. Biopsy yielded macrophages laden with Gram-negative Donovan bodies. SUMMARY AND CONCLUSION: A diagnosis of vulvar and perianal donovanosis was reached; the patient decided to terminate the pregnancy and was treated with azithromycin, which led to clinical resolution.
Hypertrophic donavanosis in a young pregnant woman / C.A. Liverani, D. Lattuada , S. Mangano, C. Pignatari, D. Puglia, E. Monti, G. Bolis,. - In: JOURNAL OF PEDIATRIC AND ADOLESCENT GYNECOLOGY. - ISSN 1083-3188. - 25:4(2012 Aug), pp. e81-e83. [10.1016/j.jpag.2011.10.002]
Hypertrophic donavanosis in a young pregnant woman
G. BolisPenultimo
2012
Abstract
BACKGROUND: Donovanosis is a chronic bacterial illness, progressive and indolent, which normally attacks the skin and mucous membranes in the genital and perigenital regions. CASE: An 18-year-old pregnant female presented with large, hypertrophic lesions in the ano-genital region. HIV serology was negative. Pap smear revealed a CIN 1 associated with HPV infection. Biopsy yielded macrophages laden with Gram-negative Donovan bodies. SUMMARY AND CONCLUSION: A diagnosis of vulvar and perianal donovanosis was reached; the patient decided to terminate the pregnancy and was treated with azithromycin, which led to clinical resolution.
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