We assessed the short-term outcome of percutaneous coronary ultrasound thrombolysis (CUT) for high-risk thrombus-containing lesions in native coronaries in the setting of acute coronary syndromes (ACS). Data were prospectively collected in a multicenter (n = 32) registry of consecutive ACS patients. The study population (n = 126) had mostly (84%) totally occluded vessels. The mean age of clot was 5.7 +/- 9.5 days (range, 0-60 days). CUT (41 kHz, 18 W) led to device success in 112 (89%) patients, with a residual stenosis of 69% +/- 20%. Adjunct PTCA or stenting was used in 97% of the patients. Procedural success was achieved in 124 (98%) patients, with a final residual stenosis of 6% +/- 10%. There were no major adverse clinical events during hospitalization. Ultrasound thrombolysis is a feasible procedure that offers a safe and probably effective adjuvant device solution for the treatment of high-risk, thrombus-containing lesions in the native coronary arteries.
|Titolo:||Percutaneous transluminal therapeutic ultrasound for high-risk thrombus-containing lesions in native coronary arteries|
BARTORELLI, ANTONIO LUCA GUIDO (Secondo)
|Parole Chiave:||Acolysis; Acute coronary syndromes; Coronary ultrasound thrombolysis; Percutaneous coronary intervention; Thrombotic lesion|
|Settore Scientifico Disciplinare:||Settore MED/11 - Malattie dell'Apparato Cardiovascolare|
|Data di pubblicazione:||gen-2002|
|Digital Object Identifier (DOI):||10.1002/ccd.2050|
|Appare nelle tipologie:||01 - Articolo su periodico|