BACKGROUND: A possible and neglected concern in women with endometriosis undergoing IVF is the potential risk of progression of the disease. We set up a prospective study mainly aimed at evaluating the impact of IVF on endometriosis-related symptoms. MATERIALS AND METHODS: Women with surgical or echographic diagnosis of endometriosis and selected for IVF were included. In the month preceding the IVF attempt and at a second evaluation 3-6 months after the cycle, women who did not get pregnant underwent clinical assessment and transvaginal ultrasonography. Each patient was requested to complete a questionnaire on the presence, severity and modifications of endometriosis-related symptoms before and after the IVF cycle. RESULTS: Overall, 64 patients completed the study protocol. The Biberoglu-Behrman Scores and the Verbal Rate Scales for dysmenorrhea, dispareunia and chronic pelvic pain did not worsen after the procedure. Other endometriosis-related symptoms also did not change. There was no modification in size and number of endometriomas and deep peritoneal nodules. The number (%) of women reporting general improvement and worsening were 14 (22%) and 7 (11%), respectively. CONCLUSIONS: IVF does not expose women to a consistent risk of endometriosis-related symptoms progression.
IVF and endometriosis-related symptom progression : insights from a prospective study / L. Benaglia, E. Somigliana, G. Santi, C. Scarduelli, G. Ragni, L. Fedele. - In: HUMAN REPRODUCTION. - ISSN 0268-1161. - 26:9(2011 Sep), pp. 2368-2372.
|Titolo:||IVF and endometriosis-related symptom progression : insights from a prospective study|
BENAGLIA, LAURA (Primo)
SOMIGLIANA, EDGARDO (Secondo)
FEDELE, LUIGI (Ultimo)
|Parole Chiave:||Endometriosis; endometriosis-related symptoms; IVF|
|Settore Scientifico Disciplinare:||Settore MED/40 - Ginecologia e Ostetricia|
|Data di pubblicazione:||set-2011|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1093/humrep/der208|
|Appare nelle tipologie:||01 - Articolo su periodico|