On the basis of MEDLINE and manual searches, we examined the main papers in the English literature regarding risk factors for spontaneous (i.e. not related to fertility drug use) multiple births. The constant frequency of monozygotic (MZ) pregnancies over time and in different geographical areas suggests that the determination of MZ twins is largely unchanged over time, and that a genetic mechanism may have a role. In contrast, temporal and geographical trends observed in dizygotic (DZ) pregnancies suggest that environmental factors play a role in determining this condition. At present, maternal age and hereditary components are the best-defined determinants for spontaneous multiple births.

The epidemiology of multiple births / R. Bortolus, F. Parazzini, L. Chatenoud, G. Benzi, M. M. Bianchi, A. Marini. - In: HUMAN REPRODUCTION UPDATE. - ISSN 1355-4786. - 5:2(1999), pp. 179-187. [10.1093/humupd/5.2.179]

The epidemiology of multiple births

F. Parazzini;
1999

Abstract

On the basis of MEDLINE and manual searches, we examined the main papers in the English literature regarding risk factors for spontaneous (i.e. not related to fertility drug use) multiple births. The constant frequency of monozygotic (MZ) pregnancies over time and in different geographical areas suggests that the determination of MZ twins is largely unchanged over time, and that a genetic mechanism may have a role. In contrast, temporal and geographical trends observed in dizygotic (DZ) pregnancies suggest that environmental factors play a role in determining this condition. At present, maternal age and hereditary components are the best-defined determinants for spontaneous multiple births.
Epidemiology; Multiple births; Risk factors
Settore MED/40 - Ginecologia e Ostetricia
1999
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/206389
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