Comparison of placebo and bromocriptine in the treatment of patients with normoprolactinemic amenorrhoea

Fourteen women with normoprolactinaemic amenorrhoea were treated with bromocriptine (2 . 5 mg twice daily) for a period ranging from 4 to 17 weeks, while a matched group of 19 amenorrhoeic women were treated with a placebo 8one tablet twice daily) for 4 to 12 weeks. About half of the patients in both groups had at least one episode of vaginal bleeding during treatment. There was no clear difference in the menstrual and ovulatory pattern between placebo and bromocriptine groups.