Background: Few data exists about relationship between respiratory function and different types of air particulates. Aim: To relate fine particles concentrations to children's respiratory function and inflammation. Methods: We selected two schools in Milan, school 1 located near a large park and school 2 downtown. From September 23th to October 3rd 2008, we sampled in and outdoor PM1, PM2,5 and PM10 (mcg/m3) by Optical Particle Counters (OPC 1,107 environcheck and OPC 1,108 dustcheck). We enrolled 232 children; 149 attending school 1, 83 school 2. All underwent spirometry and exhaled fraction of nitric oxide (FeNO) dosage. Results: Fine particles [mean (SD)] are significantly higher in school 2, except schooltime (7:30-18:30) indoor PM10, that increases in both schools (table). Respiratory function is normal in all children but the percentage values (mean [SD] of FEV1, FVC and PEF are different in the two schools (106,1 [11,85] vs 102,1 [12,87] p=0,007; 100,4 [10,77] vs 95,84 [11,45] p=0,011; 92,8 [14,62] vs 88,6 [13,63] p=0,31). Mean (SD) concentration of FeNO (ppb) is normal in both (14,5[9,16] vs 17,1 [12,7] p=0,456). Conclusion: Although PM10 indoor is higher in school 1, respiratory function is better. PM10 couldn't be the most useful indicator of air quality and its effects on children pulmunary health.
Fine particles and children's respiratory function in two primary schools in Milan, Italy / M. Giovannini. ((Intervento presentato al 3. convegno WHO International Conference on Children's Health and The Environment tenutosi a Busan nel 2009.
Fine particles and children's respiratory function in two primary schools in Milan, Italy
M. GiovanniniPrimo
2009
Abstract
Background: Few data exists about relationship between respiratory function and different types of air particulates. Aim: To relate fine particles concentrations to children's respiratory function and inflammation. Methods: We selected two schools in Milan, school 1 located near a large park and school 2 downtown. From September 23th to October 3rd 2008, we sampled in and outdoor PM1, PM2,5 and PM10 (mcg/m3) by Optical Particle Counters (OPC 1,107 environcheck and OPC 1,108 dustcheck). We enrolled 232 children; 149 attending school 1, 83 school 2. All underwent spirometry and exhaled fraction of nitric oxide (FeNO) dosage. Results: Fine particles [mean (SD)] are significantly higher in school 2, except schooltime (7:30-18:30) indoor PM10, that increases in both schools (table). Respiratory function is normal in all children but the percentage values (mean [SD] of FEV1, FVC and PEF are different in the two schools (106,1 [11,85] vs 102,1 [12,87] p=0,007; 100,4 [10,77] vs 95,84 [11,45] p=0,011; 92,8 [14,62] vs 88,6 [13,63] p=0,31). Mean (SD) concentration of FeNO (ppb) is normal in both (14,5[9,16] vs 17,1 [12,7] p=0,456). Conclusion: Although PM10 indoor is higher in school 1, respiratory function is better. PM10 couldn't be the most useful indicator of air quality and its effects on children pulmunary health.Pubblicazioni consigliate
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