Posterior reversible encephalopathy syndrome is a neurological problem characterized by headache, altered mental status, focal neurological deficits, visual disorders, and seizures. The disorder is related to a number of diseases including calcineurin inhibitor therapy in solid organ transplantation. The incidence of posterior reversible encephalopathy syndrome in lung transplantation patients is unclear; probably the majority of the cases are unreported. The authors have described a case series constituted of four patients presenting posterior reversible encephalopathy syndrome after bilateral lung transplantation. The cases had in common complicated surgery and a posttransplant course characterized by hypertension, hypomagnesemia and acidosis. Invasive mechanical ventilation, calcineurin inhibitor discontinuation, aggressive antihypertensive therapy, and electrolyte regulation led to near complete recovery of symptoms

Lung transplantation and posterior reversible encephalopathy syndrome : a case series / L. Rosso, M. Nosotti, P. Mendogni, A. Palleschi, D. Tosi, M. Montoli, M. Pappalettera, P. Tarsia, L. Santambrogio. - In: TRANSPLANTATION PROCEEDINGS. - ISSN 0041-1345. - 44:7(2012 Sep), pp. 2022-2025.

Lung transplantation and posterior reversible encephalopathy syndrome : a case series

L. Rosso
Primo
;
M. Nosotti
Secondo
;
A. Palleschi;M. Montoli;L. Santambrogio
Ultimo
2012

Abstract

Posterior reversible encephalopathy syndrome is a neurological problem characterized by headache, altered mental status, focal neurological deficits, visual disorders, and seizures. The disorder is related to a number of diseases including calcineurin inhibitor therapy in solid organ transplantation. The incidence of posterior reversible encephalopathy syndrome in lung transplantation patients is unclear; probably the majority of the cases are unreported. The authors have described a case series constituted of four patients presenting posterior reversible encephalopathy syndrome after bilateral lung transplantation. The cases had in common complicated surgery and a posttransplant course characterized by hypertension, hypomagnesemia and acidosis. Invasive mechanical ventilation, calcineurin inhibitor discontinuation, aggressive antihypertensive therapy, and electrolyte regulation led to near complete recovery of symptoms
Settore MED/21 - Chirurgia Toracica
set-2012
Article (author)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/205063
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