Introduction: The feasibility and utility of a lung donor score that has been recently proposed was tested among a pool of lung donors referred to the Nord Italia Transplant program (NITp) organ procurement organization. Material and Methods: Each lung donor was assigned an Oto score including, age, smoking history, chest X-ray, secretions and ratio of arterial oxygen tension to inspired oxygen fraction (PaO2/FiO2). Based on clinical compromise, each variable received a score between 0 and 3, except for PaO 2/FiO2, which was scored between 0 and 6 given its overall relevance. Results: Throughout 2010, 201 multiorgan donors were initially considered to be potential lung donors. Among these, 59 (29.4%) eventually yielded 67 lung transplantations (named "Used group"). Among the 142 (70.6%) refused lungs, 28 were not used due to logistic or medical problems ("general exclusion" group, GE) and 114, because of poor lung function ("lung exclusion" group, LE). Median lung donor scores were 1 (range, 0 to 3), 4 (range, 2.5 to 6.5), and 7 (range, 5 to 9) in the Used, GE, and LE groups, respectively (one-way analysis of variance, P <.001). Some donors with Oto scores ≤7 worsened over time so that the score had significantly increased by the time of organ retrieval. Overall, subjects who died after lung transplantation were characterized by higher lung donor scores, (2 [1-4] versus 0.5 [0-3], P =.003). Conclusion: Our analysis suggested that the use of a donor score as a dynamic tool over the donation process was of great utility to describe and analyze a pool of lung donors.
Use of the oto lung donor score to analyze the 2010 donor pool of the nord italia transplant program / G.A. Porro, F. Valenza, S. Coppola, S. Froio, E. Benazzi, N. De Fazio, L. Santambrogio, A.M. D’Armini, M. Loy, M. Ravini, A. Lucianetti, M.P. Moretti, S. Vesconi, M. Scalamogna, L. Gattinoni. - In: TRANSPLANTATION PROCEEDINGS. - ISSN 0041-1345. - 44:7(2012 Sep), pp. 1830-1834.
|Titolo:||Use of the oto lung donor score to analyze the 2010 donor pool of the nord italia transplant program|
VALENZA, FRANCO (Secondo)
GATTINONI, LUCIANO (Ultimo)
|Settore Scientifico Disciplinare:||Settore MED/21 - Chirurgia Toracica|
Settore MED/41 - Anestesiologia
|Data di pubblicazione:||set-2012|
|Digital Object Identifier (DOI):||http://dx.doi.org/10.1016/j.transproceed.2012.06.024|
|Appare nelle tipologie:||01 - Articolo su periodico|