The development of in vitro experimental chemotherapy against P.carinii has been hindered by the lack of efficient methods for continuous cultivation of the microorganism. Various short-term systems, allowing the production of infectious forms of Pneumocystis, can be employed for in vitro experimental chemotherapy. The purpose of the present study is to describe a statistically relevant algorithmic model for the evaluation of P.carinii in short-term in vitro culture and drug screening.
Algorithmic analysis of in vitro chemotherapy against Pneumocystis carinii / C. Atzori, F. Agostoni, E. Angeli, A. Cargnel, L. Drago, M.R. Gismondo. - In: JOURNAL OF EUKARYOTIC MICROBIOLOGY. - ISSN 1066-5234. - 44:suppl. 6(1997 Nov), pp. 30S-30S. (Intervento presentato al convegno 5. International Workshops on Opportunistic Protists & 5. General Meeting of the European Concerted Action on Pneumocystis Research tenutosi a Lille nel 1997) [10.1111/j.1550-7408.1997.tb05754.x].
Algorithmic analysis of in vitro chemotherapy against Pneumocystis carinii
L. DragoPenultimo
;M.R. GismondoUltimo
1997
Abstract
The development of in vitro experimental chemotherapy against P.carinii has been hindered by the lack of efficient methods for continuous cultivation of the microorganism. Various short-term systems, allowing the production of infectious forms of Pneumocystis, can be employed for in vitro experimental chemotherapy. The purpose of the present study is to describe a statistically relevant algorithmic model for the evaluation of P.carinii in short-term in vitro culture and drug screening.
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