A soybean textured protein induced a 14% decrease of plasma-cholesterol levels after two weeks and 21% after three when substituted for animal proteins in a group of 20 patients with type-II hyperlipoproteinæmia. Comparison of soybean diet with a standard low-lipid diet in the same patients, according to a cross-over protocol, indicated that this hypocholesterolæmic effect was not due to differences in the lipid composition of the two diets. The hypothesis that a soy protein has a hypocholesterolæmic action perse is supported by the results of a subsequent experiment in 8 type-II patients in whom the addition of cholesterol (500 mg/day) to soy protein did not modify the hypocholesterolæmic response.
Soybean-protein diet in the treatment of type-II hyperlipoproteinaemia / C.R. Sirtori, E. Agradi, F. Conti, O. Mantero, E. Gatti. - In: THE LANCET. - ISSN 0140-6736. - 309:8006(1977), pp. 275-277. [10.1016/S0140-6736(77)91823-2]
Soybean-protein diet in the treatment of type-II hyperlipoproteinaemia
C.R. SirtoriPrimo
;E. AgradiSecondo
;
1977
Abstract
A soybean textured protein induced a 14% decrease of plasma-cholesterol levels after two weeks and 21% after three when substituted for animal proteins in a group of 20 patients with type-II hyperlipoproteinæmia. Comparison of soybean diet with a standard low-lipid diet in the same patients, according to a cross-over protocol, indicated that this hypocholesterolæmic effect was not due to differences in the lipid composition of the two diets. The hypothesis that a soy protein has a hypocholesterolæmic action perse is supported by the results of a subsequent experiment in 8 type-II patients in whom the addition of cholesterol (500 mg/day) to soy protein did not modify the hypocholesterolæmic response.Pubblicazioni consigliate
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