We studied 19 patients (pts) as compassionate case, with an age between 17 and 44 years (mean 29 ys), with a duration of epilepsy between 5 and 30 years, all with diagnosis of drug-resistant epilepsy. The pts were 13 with partial epilepsy, 3 with Lennox-Gastaut syndrome, 2 with multifocal partial epilepsy with non progressive brain damage and 1 with Lafora disease. All pts have been followed for a period between 12 and 40 months. In 2 (10.5%) pts we observed a complete disappearance of the seizures, and in 3 (15.8%) a greater than 50% reduction in total seizure number. Tolerance to Vigabatrin was good and no patient was withdrawn because of side effects.
VALUTAZIONE DELLA RISPOSTA A LUNGO TERMINE AL VIGABATRIN NELLE EPILESSIE FARMACO-RESISTENTI: STUDIO DI 19 CASI / R. Mai, M.P. Canevini, C. Di Marco, L. Minotti, A. Saltarelli, A. Iudice, U. Aguglia, P. Nichelli, R. Canger. - In: BOLLETTINO-LEGA ITALIANA CONTRO L'EPILESSIA. - ISSN 0394-560X. - 74(1991), pp. 203-204.
VALUTAZIONE DELLA RISPOSTA A LUNGO TERMINE AL VIGABATRIN NELLE EPILESSIE FARMACO-RESISTENTI: STUDIO DI 19 CASI
M.P. CaneviniSecondo
;R. CangerUltimo
1991
Abstract
We studied 19 patients (pts) as compassionate case, with an age between 17 and 44 years (mean 29 ys), with a duration of epilepsy between 5 and 30 years, all with diagnosis of drug-resistant epilepsy. The pts were 13 with partial epilepsy, 3 with Lennox-Gastaut syndrome, 2 with multifocal partial epilepsy with non progressive brain damage and 1 with Lafora disease. All pts have been followed for a period between 12 and 40 months. In 2 (10.5%) pts we observed a complete disappearance of the seizures, and in 3 (15.8%) a greater than 50% reduction in total seizure number. Tolerance to Vigabatrin was good and no patient was withdrawn because of side effects.
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