An association between schizophrenia and the T102C polymorphism of the gene for 5-hydroxytryptamine type 2a (5-HT2a) receptor has been reported; the proportion of allele 2 of this polymorphism is higher than expected among schizophrenic patients. We looked for an association between schizophrenia and this variant of the 5-HT2a-receptor gene in a large multicentre study.
Association between schizophrenia and T102C polymorphism of the 5-hydroxytryptamine type 2a-receptor gene. European Multicentre Association Study of Schizophrenia (EMASS) Group / J. Williams, G. Spurlock, P. McGuffin, J. Mallet, M. M. Nöthen, M. Gill, H. Aschauer, P. O. Nylander, F. Macciardi, M. J. Owen. - In: THE LANCET. - ISSN 0140-6736. - 347:9011(1996 May 11), pp. 1294-6-1296. [10.1016/S0140-6736(96)90939-3]
Association between schizophrenia and T102C polymorphism of the 5-hydroxytryptamine type 2a-receptor gene. European Multicentre Association Study of Schizophrenia (EMASS) Group
F. MacciardiPenultimo
;
1996
Abstract
An association between schizophrenia and the T102C polymorphism of the gene for 5-hydroxytryptamine type 2a (5-HT2a) receptor has been reported; the proportion of allele 2 of this polymorphism is higher than expected among schizophrenic patients. We looked for an association between schizophrenia and this variant of the 5-HT2a-receptor gene in a large multicentre study.
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