A concise discussion of the role of different geometrical conformational states in the process of self-assembling of gangliosides is given. The report focuses on the effects of the geometrical variations occurring in the head group region of gangliosides as reflected on the geometrical properties of the whole assembly. Collective phenomena happening at the water interfacial region are found to be coupled to the phase transition of the lipid moiety, that is, to the well-known order-disorder conformational transition involving the hydrophobic tails. The possible biological relevance of the head group bistability is envisaged

Cooperative behavior of ganglioside molecules in model systems / P. Brocca, L. Cantù, M. Corti, E. Del Favero, A. Raudino. - In: NEUROCHEMICAL RESEARCH. - ISSN 0364-3190. - 27:7-8(2002 Aug), pp. 559-563.

Cooperative behavior of ganglioside molecules in model systems

P. Brocca
Primo
;
L. Cantù
Secondo
;
M. Corti;E. Del Favero
Penultimo
;
2002

Abstract

A concise discussion of the role of different geometrical conformational states in the process of self-assembling of gangliosides is given. The report focuses on the effects of the geometrical variations occurring in the head group region of gangliosides as reflected on the geometrical properties of the whole assembly. Collective phenomena happening at the water interfacial region are found to be coupled to the phase transition of the lipid moiety, that is, to the well-known order-disorder conformational transition involving the hydrophobic tails. The possible biological relevance of the head group bistability is envisaged
Ganglioside aggregates; Micelles; Surface phase transition
Settore FIS/07 - Fisica Applicata(Beni Culturali, Ambientali, Biol.e Medicin)
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Utilizza questo identificativo per citare o creare un link a questo documento: https://hdl.handle.net/2434/20140
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