Considérations sur l'utilisation du renouvellement du plasma dans le traitement du Syndrome de Raynaud

Seven subjects affected by svere Raynaud's phenomenon, unresponsive to the usual medical treatment, were treated with plasma exchange. Three patients had some immunological tests positive, without showing a specific immunologic disease. Two patients had been submitted to thorcic gangliectomy with poor reults and showed digital ulcers. Plasma exchange was done every other day for 3 times, measuring blood and plasma viscosity before, immediately after and a week after the treatment. In two patients out of seven a definite improvement of symptoms was observed, with healing of ulcers. A haemodynamic evaluation with doppler velocimetry was done in all patients, shiwing a better blood flow in two cases. A transitenblood viscosity decrease was observed.