An investigation was carried out into the possible effects of ampicillin and a sulbactam/ampicillin combination on the immune system of healthy subjects. The following immunological variables were compared before and after antibiotic therapy: proliferation response of peripheral mononuclear cells to phytohaemagglutinin; variation of T- and B-lymphocytes; dosage of interleukin-2; and production of immunoglobulin A. The data obtained did not demonstrate any immunodepressive activity by either ampicillin or the sulbactam/ampicillin combination.
Effect of ampicillin and sulbactam/ampicillin on the immunesystem / M.R. Gismondo, G. Chisari, A.M. Lo Bue. - In: JOURNAL OF INTERNATIONAL MEDICAL RESEARCH. - ISSN 0300-0605. - 19:suppl. 1(1991), pp. 24A-28A.
Effect of ampicillin and sulbactam/ampicillin on the immunesystem
M.R. GismondoPrimo
;
1991
Abstract
An investigation was carried out into the possible effects of ampicillin and a sulbactam/ampicillin combination on the immune system of healthy subjects. The following immunological variables were compared before and after antibiotic therapy: proliferation response of peripheral mononuclear cells to phytohaemagglutinin; variation of T- and B-lymphocytes; dosage of interleukin-2; and production of immunoglobulin A. The data obtained did not demonstrate any immunodepressive activity by either ampicillin or the sulbactam/ampicillin combination.Pubblicazioni consigliate
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