In our study we considered the possible interference of cefetamet-pivoxil with the intestinal microflora. We used 60 germ-free mice in which an intestinal microflora similar to the human one had been implanted. They were treated with 14.3 mg/Kg/die (standard dose) and a 28.6 mg/kg/die (daily dose) of cefetamet-pivoxil by oral route. The results obtained in vivo proved that cefetamet-pivoxil at therapeutic doses does not influence the normal intestinal microflora.
Impact of Cefetamet-Pivoxil on intestinal microflora: in vivo study / M.R. Gismondo, L. Drago, A. Lombardi, C. Fassina. - In: JOURNAL OF CHEMOTHERAPY. - ISSN 1120-009X. - 6:4(1994), pp. 246-250.
Impact of Cefetamet-Pivoxil on intestinal microflora: in vivo study
M.R. Gismondo;
1994
Abstract
In our study we considered the possible interference of cefetamet-pivoxil with the intestinal microflora. We used 60 germ-free mice in which an intestinal microflora similar to the human one had been implanted. They were treated with 14.3 mg/Kg/die (standard dose) and a 28.6 mg/kg/die (daily dose) of cefetamet-pivoxil by oral route. The results obtained in vivo proved that cefetamet-pivoxil at therapeutic doses does not influence the normal intestinal microflora.Pubblicazioni consigliate
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