Aim: to evaluate the prevalence of abnormal spiral arteries modification (ASAM) in stillbirths and its anatomo-clinical correlations. Methods: 203 placentas of stillbirth ≥20 weeks of gestation were analysed. Results: ASAM was present in 69/203 cases (33.9%). The only maternal characteristic that significantly differed in ASAM versus normal spiral arteries modification (NSAM) cases was the pre-pregnancy body mass index (25.9±6.1 and 23.1±4.2 kg/m(2) respectively) with 15.9% of obesity in ASAM mothers versus 5.2% in NSAM (p=0.02). Conclusion: given the association between obesity and adverse pregnancy outcome, our data suggest that counselling obese women to lose weight before pregnancy becomes increasingly imperative.
Abnormal spiral arteries modification in stillbirths : the role of maternal pre-pregnancy body mass index / L. Avagliano, A.M. Marconi, S. Romagnoli, G.P. Bulfamante. - In: THE JOURNAL OF MATERNAL-FETAL & NEONATAL MEDICINE. - ISSN 1476-7058. - 25:12(2012 Dec), pp. 2789-2792. [10.3109/14767058.2012.705395]
Abnormal spiral arteries modification in stillbirths : the role of maternal pre-pregnancy body mass index
L. AvaglianoPrimo
;A.M. MarconiSecondo
;S. RomagnoliPenultimo
;G.P. BulfamanteUltimo
2012
Abstract
Aim: to evaluate the prevalence of abnormal spiral arteries modification (ASAM) in stillbirths and its anatomo-clinical correlations. Methods: 203 placentas of stillbirth ≥20 weeks of gestation were analysed. Results: ASAM was present in 69/203 cases (33.9%). The only maternal characteristic that significantly differed in ASAM versus normal spiral arteries modification (NSAM) cases was the pre-pregnancy body mass index (25.9±6.1 and 23.1±4.2 kg/m(2) respectively) with 15.9% of obesity in ASAM mothers versus 5.2% in NSAM (p=0.02). Conclusion: given the association between obesity and adverse pregnancy outcome, our data suggest that counselling obese women to lose weight before pregnancy becomes increasingly imperative.File | Dimensione | Formato | |
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