The interference of chlorpromazine (CPZ) and several preincubated CPZ metabolites on the lymphocyte absorption of antibodies directed against HLA-A1 and other nonrelated HLA specificities were investigated. Both CPZ and metabolites 7-OH-, Nor1-, and Nor2-CPZ were found to interfere with the specific absorption of anti-HLA-A1 antibodies. The meaning of such a result is discussed.
Interference between anti-HLA antibodies and CPZ metabolites / E. Smeraldi, R. Scorza-Smeraldi, G. Fabio, F. Negri. - In: PSYCHOPHARMACOLOGY. - ISSN 0033-3158. - 67:1(1980 Jan), pp. 87-9-89.
Interference between anti-HLA antibodies and CPZ metabolites
R. Scorza-Smeraldi;G. Fabio;
1980
Abstract
The interference of chlorpromazine (CPZ) and several preincubated CPZ metabolites on the lymphocyte absorption of antibodies directed against HLA-A1 and other nonrelated HLA specificities were investigated. Both CPZ and metabolites 7-OH-, Nor1-, and Nor2-CPZ were found to interfere with the specific absorption of anti-HLA-A1 antibodies. The meaning of such a result is discussed.
File in questo prodotto:
Non ci sono file associati a questo prodotto.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
