Previous studies have documented the high frequency of thrombosis and fetal loss in patients with lupus nephritis and antiphospholipid (aPL) antibodies, but there is little information on the impact of aPL antibodies on the outcome of lupus nephritis. The aims of this study are to evaluate the prevalence of aPL antibodies in patients with lupus nephritis and assess their prognostic value for thrombosis and pregnancy morbidity and impact on long-term renal outcome.
Antiphospholipid antibodies are associated with an increased risk for chronic renal insufficiency in patients with lupus nephritis / G. Moroni, D. Ventura, P. Riva, P. Panzeri, S. Quaglini, G. Banfi, P. Simonini, R. Bader, P. L. Meroni, C. Ponticelli. - In: AMERICAN JOURNAL OF KIDNEY DISEASES. - ISSN 0272-6386. - 43:1(2004 Jan), pp. 28-36. [10.1053/j.ajkd.2003.09.011]
Antiphospholipid antibodies are associated with an increased risk for chronic renal insufficiency in patients with lupus nephritis
R. Bader;P. L. Meroni;
2004
Abstract
Previous studies have documented the high frequency of thrombosis and fetal loss in patients with lupus nephritis and antiphospholipid (aPL) antibodies, but there is little information on the impact of aPL antibodies on the outcome of lupus nephritis. The aims of this study are to evaluate the prevalence of aPL antibodies in patients with lupus nephritis and assess their prognostic value for thrombosis and pregnancy morbidity and impact on long-term renal outcome.
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