In order to improve our understanding of the molecular pathways that mediate tumor proliferation and angiogenesis, and to evaluate the biological response to anti-angiogenic therapy, we analyzed the changes in the protein profile of glioblastoma in response to treatment with recombinant human Platelet Factor 4-DLR mutated protein (PF4-DLR), an inhibitor of angiogenesis.
Anti-angiogenic therapy induces integrin-linked kinase 1 up-regulation in a mouse model of glioblastoma / C. Verpelli, G. Bertani, V. Cea, M. Patti, A. Bikfalvi, L. Bello, C. Sala. - In: PLOS ONE. - ISSN 1932-6203. - 5:10(2010). [10.1371/journal.pone.0013710]
Anti-angiogenic therapy induces integrin-linked kinase 1 up-regulation in a mouse model of glioblastoma
L. Bello;
2010
Abstract
In order to improve our understanding of the molecular pathways that mediate tumor proliferation and angiogenesis, and to evaluate the biological response to anti-angiogenic therapy, we analyzed the changes in the protein profile of glioblastoma in response to treatment with recombinant human Platelet Factor 4-DLR mutated protein (PF4-DLR), an inhibitor of angiogenesis.
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