The growth of gliomas depends on the balance of factors stimulating or inhibiting angiogenesis, tumor cell invasion and proliferation. The administration of endogenous inhibitors to experimental human gliomas in animal models resulted in a significant inhibition of tumor growth. It is becoming apparent that resistance can develop over time to many types of endogenous inhibitors and seems to be influenced by the tumor type and system of delivery.
Long-term inhibition of glioma growth by systemic administration of human PEX / M. Pluderi, V. Lucini, D. Caronzolo, M. Pannacci, F. Costa, G. Carrabba, C. Giussani, S. Grosso, F. Colleoni, F. Scaglione, R. Villani, A. Bikfalvi, L. Bello. - In: JOURNAL OF NEUROSURGICAL SCIENCES. - ISSN 0390-5616. - 47:2(2003 Jun), pp. 69-78.
Long-term inhibition of glioma growth by systemic administration of human PEX
V. Lucini;F. Scaglione;L. Bello
2003
Abstract
The growth of gliomas depends on the balance of factors stimulating or inhibiting angiogenesis, tumor cell invasion and proliferation. The administration of endogenous inhibitors to experimental human gliomas in animal models resulted in a significant inhibition of tumor growth. It is becoming apparent that resistance can develop over time to many types of endogenous inhibitors and seems to be influenced by the tumor type and system of delivery.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
