In 24 patients with stable spontaneous and effort-related angina, ischemic episodes at rest were not preceded by changes in circulatory variables (heart rate, systemic and pulmonary arterial pressures) that may raise the myocardial oxygen consumption. We interpreted these episodes as caused by critical and reversible coronary flow reduction at the site of a stenotic lesion, and evaluated the clinical efficacy of nifedipine and propranolol in the treatment of this condition.
Superior efficacy of propranolol versus nifedipine in double-component angina, as related to different influences on coronary vasomotility / N. De Cesare, A. Bartorelli, F. Fabbiocchi, A. Folli, A. Loaldi, P. Montorsi, A. Polese, M. Guazzi. - In: THE AMERICAN JOURNAL OF MEDICINE. - ISSN 0002-9343. - 87:1(1989 Jul), pp. 15-21-21.
Superior efficacy of propranolol versus nifedipine in double-component angina, as related to different influences on coronary vasomotility
A. BartorelliSecondo
;A. Loaldi;P. Montorsi;
1989
Abstract
In 24 patients with stable spontaneous and effort-related angina, ischemic episodes at rest were not preceded by changes in circulatory variables (heart rate, systemic and pulmonary arterial pressures) that may raise the myocardial oxygen consumption. We interpreted these episodes as caused by critical and reversible coronary flow reduction at the site of a stenotic lesion, and evaluated the clinical efficacy of nifedipine and propranolol in the treatment of this condition.
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