The members of the T-box gene family share a highly conserved DNA binding domain named the T-domain, and important developmental functions. Here we report the cloning of chicken Tbr1 and of murine and chicken Tbr2 (orthologs of the Xenopus eomesodermin gene), the mapping of the murine Tbr2 to chromosome 9, and their pattern of expression during mouse and chick embryogenesis. Both Tbr 1 and 2 have a restricted and conserved domain of expression in the telencephalic pallium of the two species. Chick Tbr2 has a specific and dynamic expression in the gastrulating embryo.
Expression pattern of the Tbr-2 (Eomesodermin) gene during mouse and chick brain development / A. Bulfone, S. Martinez, V. Marigo, M. Campanella, A. Basile, N. Quaderi, C. Gattuso, J.L.R. Rubenstein, A. Ballabio. - In: MECHANISMS OF DEVELOPMENT. - ISSN 0925-4773. - 84:1-2(1999 Jun), pp. 133-138.
Expression pattern of the Tbr-2 (Eomesodermin) gene during mouse and chick brain development
A. Basile;
1999
Abstract
The members of the T-box gene family share a highly conserved DNA binding domain named the T-domain, and important developmental functions. Here we report the cloning of chicken Tbr1 and of murine and chicken Tbr2 (orthologs of the Xenopus eomesodermin gene), the mapping of the murine Tbr2 to chromosome 9, and their pattern of expression during mouse and chick embryogenesis. Both Tbr 1 and 2 have a restricted and conserved domain of expression in the telencephalic pallium of the two species. Chick Tbr2 has a specific and dynamic expression in the gastrulating embryo.
Pubblicazioni consigliate
I documenti in IRIS sono protetti da copyright e tutti i diritti sono riservati, salvo diversa indicazione.
