Immunity to tetanus toxoid and polioviruses was studied in 34 (27 allografted, 7 autografted) children who underwent bone marrow transplantation (BMT). At a median time of 3 years after BMT, only one recipient was seronegative for tetanus toxoid. On the contrary 73 % of children were seronegative for at least one of the three poliovirus types and 30% for all vim types. Undetectable antibody titers were more frequently found against type 3 than the other two types. We recommend that reimmunizations of children after BMT be based on serologic tests for antibody titers.
IMMUNITY TO POLIOVIRUSES AND TETANUS AFTER BONE MARROW TRANSPLANTATION IN CHILDREN / C. Pezzini, M. Limonta, A. Rovelli, C. Uderzo, A. Locasciulli, O. Maglia, G. Masera, M. Barbi, A. Pozzi, C. Luraschi, S. Binda, A. Panuccio, F. Giordano. - In: PEDIATRIC HEMATOLOGY AND ONCOLOGY. - ISSN 0888-0018. - 11:3(1994), pp. 331-334.
IMMUNITY TO POLIOVIRUSES AND TETANUS AFTER BONE MARROW TRANSPLANTATION IN CHILDREN
M. Barbi;S. Binda;
1994
Abstract
Immunity to tetanus toxoid and polioviruses was studied in 34 (27 allografted, 7 autografted) children who underwent bone marrow transplantation (BMT). At a median time of 3 years after BMT, only one recipient was seronegative for tetanus toxoid. On the contrary 73 % of children were seronegative for at least one of the three poliovirus types and 30% for all vim types. Undetectable antibody titers were more frequently found against type 3 than the other two types. We recommend that reimmunizations of children after BMT be based on serologic tests for antibody titers.
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